An Unusual Case of Extensively Drug-Resistant (XDR) Salmonella Typhi Meningitis in Seven Month Old

Authors

  • Asha Ramesh Department of Paediatric Medicine, Liaquat University Hospital, Hyderabad, Pakistan
  • Chetan Das Department of Paediatric Medicine, Liaquat University Hospital, Hyderabad, Pakistan
  • Muhammad Touseef Department of Paediatric Medicine, Liaquat University Hospital, Hyderabad, Pakistan
  • Ainey Razzak Department of Paediatric Medicine, Liaquat University Hospital, Hyderabad, Pakistan
  • Lareb Soomro Department of Paediatric Medicine, Liaquat University Hospital, Hyderabad, Pakistan
  • Aiysha Farhat Department of Paediatric Medicine, Liaquat University Hospital, Hyderabad, Pakistan

DOI:

https://doi.org/10.71158/ajhs.v1i4.76

Keywords:

Salmonella typhi , meningitis, extensively drug resistant

Abstract

Meningitis is unusual complication of salmonella typhi, having a high mortality rate and neurological issues, making early identification & treatment absolutely essential. Its prevalence is 6 % with unfortunate deteriorating neurological sequence. Patients of bacterial meningitis mostly presented with headache, fever, ALOC & neck rigidity. CSF culture is used to make absolute diagnosis. In this case report, a case of 7 month old male baby is presented who had XDR-Salmonella typhi meningitis, an uncommon incident of salmonella meningitis manifested with enteric fever that was unresponsive to early antibiotic therapy. It was then treated with imipenem and azithromycin as the typhi strain was sensitive to these drugs as per culture report.

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Published

15-01-2025

How to Cite

Asha Ramesh, Chetan Das, Muhammad Touseef, Ainey Razzak, Lareb Soomro, & Aiysha Farhat. (2025). An Unusual Case of Extensively Drug-Resistant (XDR) Salmonella Typhi Meningitis in Seven Month Old . Avicenna Journal of Health Sciences, 1(4). https://doi.org/10.71158/ajhs.v1i4.76